| pos. | Title | Gross | |
|---|---|---|---|
| 1 |  | Harry Potter and the Half Blood Prince (2009) | £50,657,586 |
| 2 |  | Ice Age: Dawn of the Dinosaurs (2009) | £34,607,578 |
| 3 |  | Up (2009) | £34,284,193 |
| 4 |  | Slumdog Millionaire (2008) | £31,643,207 |
| 5 |  | The Twilight Saga: New Moon (2009) | £26,272,710 |
| 6 |  | The Hangover (2009) | £21,620,272 |
| 7 |  | Star Trek (2009) | £21,188,170 |
| 8 |  | Monsters Vs. Aliens (2009) | £21,113,359 |
| 9 |  | Transformers: Revenge of the Fallen (2009) | £20,894,050 |
| 10 |  | Night At the Museum 2 (2009) | £19,661,121 |
| 11 |  | A Christmas Carol (2009) | £19,595,369 |
| 12 |  | 2012 (2009) | £19,354,774 |
| 13 |  | Angels and Demons (2009) | £18,509,160 |
| 14 |  | Avatar (2009) | £18,404,659 |
| 15 |  | Bolt (2009) | £17,745,776 |
| 16 |  | X-Men Origins: Wolverine (2009) | £16,166,926 |
| 17 |  | Brüno (2009) | £15,369,471 |
| 18 |  | Marley and Me (2009) | £15,123,080 |
| 19 |  | Terminator Salvation (2009) | £14,114,589 |
| 20 |  | Fast and Furious (2009) | £13,539,304 |