| pos. | Title | Gross | |
|---|---|---|---|
| 1 |  | Black Panther (2018) | $700,006,415 |
| 2 |  | Avengers: Infinity War (2018) | $678,809,000 |
| 3 |  | Incredibles 2 (2018) | $608,574,642 |
| 4 |  | Jurassic World: Fallen Kingdom (2018) | $416,736,650 |
| 5 |  | Deadpool 2 (2018) | $323,220,782 |
| 6 |  | The Grinch (2018) | $265,457,730 |
| 7 |  | Jumanji: Welcome to the Jungle (2017) | $235,532,087 |
| 8 |  | Mission:Impossible - Fallout (2018) | $220,087,856 |
| 9 |  | Ant-Man and the Wasp (2018) | $216,640,060 |
| 10 |  | Solo: A Star Wars Story (2018) | $213,762,989 |
| 11 |  | Venom (2018) | $213,116,023 |
| 12 |  | A Star Is Born (2018) | $201,033,452 |
| 13 |  | Bohemian Rhapsody (2018) | $189,207,042 |
| 14 |  | Aquaman (2018) | $189,048,186 |
| 15 |  | A Quiet Place (2018) | $187,954,270 |
| 16 |  | Ralph Breaks the Internet: Wreck-It Ralph 2 (2018) | $175,907,767 |
| 17 |  | Hotel Transylvania 3: Summer Vacation (2018) | $168,784,127 |
| 18 |  | Crazy Rich Asians (2018) | $165,269,987 |
| 19 |  | Halloween (2018) | $159,335,555 |
| 20 |  | Fantastic Beasts: The Crimes of Grindelwald (2018) | $156,549,701 |