| pos. | Title | Gross | |
|---|---|---|---|
| 1 |  | No Time To Die (2021) | £96,555,145 |
| 2 |  | Spider-Man: No Way Home (2021) | £69,849,930 |
| 3 |  | Dune (2021) | £21,800,000 |
| 4 |  | Shang-Chi and the Legend of the Ten Rings (2021) | £21,134,754 |
| 5 |  | Peter Rabbit 2: The Runaway (2021) | £20,312,000 |
| 6 |  | Black Widow (2021) | £18,841,022 |
| 7 |  | Venom: Let There Be Carnage (2021) | £18,027,072 |
| 8 |  | Free Guy (2021) | £16,786,917 |
| 9 |  | Fast and Furious 9 (2021) | £16,452,880 |
| 10 |  | Eternals (2021) | £14,869,370 |
| 11 |  | The Suicide Squad (2021) | £14,200,000 |
| 12 |  | Space Jam: A New Legacy (2021) | £12,825,199 |
| 13 |  | Jungle Cruise (2021) | £12,488,302 |
| 14 |  | A Quiet Place: Part II (2021) | £11,547,774 |
| 15 |  | Ghostbusters: Afterlife (2021) | £11,053,586 |
| 16 |  | The Addams Family 2 (2021) | £10,200,000 |
| 17 |  | The Croods: A New Age (2020) | £9,882,749 |
| 18 |  | Cruella (2021) | £9,456,047 |
| 19 |  | The Conjuring: The Devil Made Me Do It (2021) | £9,400,000 |
| 20 |  | House of Gucci (2021) | £8,753,878 |