| pos. | Title | Gross | |
|---|---|---|---|
| 1 |  | Harry Potter and the Deathly Hallows Part 2 (2011) | $381,011,219 |
| 2 |  | Transformers: Dark of the Moon (2011) | $352,358,779 |
| 3 |  | The Twilight Saga: Breaking Dawn Part 1 (2011) | $275,530,738 |
| 4 |  | The Hangover Part II (2011) | $254,455,986 |
| 5 |  | Pirates of the Caribbean: On Stranger Tides (2011) | $241,063,875 |
| 6 |  | Fast Five (2011) | $209,805,005 |
| 7 |  | Cars 2 (2011) | $191,402,180 |
| 8 |  | Thor (2011) | $181,015,141 |
| 9 |  | Rise of the Planet of the Apes (2011) | $176,698,086 |
| 10 |  | Captain America: The First Avenger (2011) | $176,636,816 |
| 11 |  | Bridesmaids (2011) | $169,076,745 |
| 12 |  | Kung-Fu Panda 2 (2011) | $165,230,261 |
| 13 |  | The Help (2011) | $159,625,720 |
| 14 |  | X-Men: First Class (2011) | $146,405,371 |
| 15 |  | Puss In Boots (2011) | $145,483,661 |
| 16 |  | Rio (2011) | $143,613,651 |
| 17 |  | The Smurfs (2011) | $142,614,158 |
| 18 |  | Mission:Impossible - Ghost Protocol (2011) | $131,806,086 |
| 19 |  | Sherlock Holmes: A Game of Shadows (2011) | $130,903,746 |
| 20 |  | Super 8 (2011) | $126,975,169 |